MEERVOUD grant Paula da Costa Martins

THE HAGUE, THE NETHERLANDS (01-09-2012) - Paula da Costa Martins, Assistant Professor at the dept. of Cardiology received a grant of the Netherlands Organisation for Scientific Research (NWO) on her research proposal: “Post-transcriptional regulation of autophagy: MiR-216a as a cell death-regulating microRNA during myocardial repair”.

With a MEERVOUD grant (“MEER Vrouwelijke Onderzoekers als UD”) NWO aims to increase the number of women in the position of university lecturer. The MEERVOUD grant finances a temporary lecturer position, with the added guarantee to proceed to a scientific position within the research institute. The grant is awarded for a minimum of 2 and a maximum of 4 years.
Paula da Costa Martins will use her MEERVOUD grant to investigate the role of miR-216a in cell death during myocardial repair, and to identify miRNAs that are involved in regulating autophagy in cardiomyocytes. Her granted research proposal considers the following key objectives: 1) identify genes that are directly regulated by miR-216a and 2) define the role of miR-216a regulating cell death in ischemic heart disease; 3) establish the therapeutic value of miR-216 silencing in cardiac disease and 4) identify autophagy-regulating microRNAs by high-throughput sequencing.